One of the best anti wrinkle cream ingredients and most common found in wrinkle creams is a vitamin A compound known as retinol. Retinol is an antioxidant – in fact, it is the first antioxidant to be used in wrinkle creams. Antioxidants work in the body by neutralizing the free radicals that break down the skin’s cells and cause wrinkles. It is important to note that vitamin A derivatives should be avoided if you are pregnant or trying to become pregnant. Another great vitamin for your skin is vitamin C. This is a natural skin brightener, which will also give you a more youthful look if it is found in your wrinkle cream.